Daily archives: 14. March 2022

1 post

Study on casirivimab and imdevimab

RECOVERY Collaborative Group (ed.): Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled,open-label, platform trial, in: The Lancet 339, Issue 10325 (February 12, 2022), S. 665-676, online in: https://doi.org/10.1016/S0140-6736(22)00163-5. Summary of the study “Background Casirivimab and imdevimab are non-competing monoclonal antibodies that bind to two different sites on the receptor binding domain of the SARS-CoV-2 spike glycoprotein, blocking viral entry into host cells. The authors aimed to evaluate the efficacy and safety of casirivimab and imdevimab administered in combination in patients admitted to hospital with COVID-19. Methods RECOVERY is a randomised, controlled, open-label platform trial […]