Paul-Ehrlich-Institut: Sicherheitsbericht. Verdachtsfälle von Nebenwirkungen und Impfkomplikationen nach Impfung zum Schutz vor COVID-19 seit Beginn der
Impfkampagne am 27.12.2020 bis zum 31.12.2021, Langen, February 7, 2022.
The Paul Ehrlich Institute (PEI), as the Federal Institute for Vaccines and Biomedical Products, reports on suspected cases of adverse reactions or vaccine complications reported from Germany in temporal association with vaccination with the mRNA vaccines Comirnaty (BioNTech Manufacturing GmbH) and Spikevax (MODERNA BIOTECH SPAIN, S.L.) and the vector vaccines Vaxzevria (AstraZeneca AB) and COVID-19 Vaccine Janssen for protection against COVID-19 from the start of the vaccination campaign on Dec. 27, 2020, to Dec. 31, 2021. According to the Robert Koch Institute (RKI), 148. 760,720 vaccinations were given, including 110,533,639 vaccinations with Comirnaty, 21,912,123 vaccinations with Spikevax, 12,738,494 vaccinations with Vaxzevria and 3,576,464 vaccinations with COVID-19 Vaccine Janssen. A total of 244,576 suspected adverse event cases were reported after Comirnaty, Spikevax, Vaxzevria, and COVID-19 Vaccine Janssen. The reporting rate was 1.64 reports per 1,000 vaccine doses for all vaccines combined, and 0.20 reports per 1,000 vaccine doses for serious reactions.