Daily archives: 28. November 2022

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Respiratory Administration of Antibodies

Michael S. Piepenbrink, Jun-Gyu Park et al.: Potent universal beta-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing monoclonal antibody, in: PLOS Pathogens Vol. 18, Issue 7 (July 21, 2022) p. e101691, online in: https://doi.org/10.1371/journal.ppat.1010691. Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) marks the third novel β-coronavirus to cause significant human mortality in the last two decades. Although vaccines are available, too few have been administered worldwide to keep the virus in check and to prevent mutations leading to immune escape. To determine if antibodies could be identified with universal coronavirus activity, plasma from […]