Daily archives: 7. April 2022

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T cell response to omicron

Vivek Naranbhai et al.: T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all prior infected and vaccinated individuals, in: medRxiv, online in: https://doi.org/10.1101/2022.01.04.21268586. Abstract The SARS-CoV-2 Omicron variant (B.1.1.529) contains mutations that mediate escape from infection- and vaccine-induced antibody responses, although the extent to which these substitutions in spike and non-spike proteins affect T cell recognition is unknown. In their article the authors show that T cell responses in individuals with prior infection, vaccination, both prior infection and vaccination, and boosted vaccination are largely preserved to Omicron spike and non-spike proteins. However, the authors […]